Sample courtesy of Dr Lionel Willat, Department of Cytogenetics, Addenbrookes Hospital, Cambridge, UK
Leica CW4000 Karyotyping Continued
 
   
  • No requirement to delete background during thresholding (detection of chromosome boundaries). CW4000 handles images intelligently – there is no risk of permanent deletion of telomeres and satellites by “over thresholding”, and you gain total confidence in your results.

  • Human and non human karyotyping included as standard – no need to buy an extra module for Research projects. Karyogram layouts are included for rat, mouse, cattle, wheat, pig and human. New layouts are simple to generate.

 

   
  • The ability to effortlessly karyotype FISH images (either human or non human) using the inverted counterstain image (requires CGH option).

  • Extreme Ratio Detection - allows the operator to display only red/green pixels from a fluorochrome above or below certain intensity (ratio) levels. This can be used in Cross Species painting experiments to examine the image for areas of homology between two different species.

  • Extensive karyotyping enhancement and presentation tools, presented in a logical, workflow approach.

 
Comparison of chromosomes captured using a standard video CCD camera and the high resolution Leica DC500 digital camera