Courtesy of Dr Cristina Montagna and Dr Thomas Reid, National Cancer Institute/NIH, Bethesda, USA
Leica CW4000 CGH
 
   
The combination of accurate, efficient karyotyping with advanced CGH analysis tools, provides the most powerful CGH system commercially available. Additionally, the incorporation of high resolution Digital Camera technology delivers an unrivalled high resolution CGH system with unique interactive Ratio Normalisation facility. The streamlined CW4000 karyotyping tools make the system suitable either for research or routine studies.

 

    
Leica CGH Offers:

  • Accurate classification of inverted DAPI metaphases - adaptable to multiple species including human, mouse and rat.

  • Fully automatic calculation of ratio to values and profiles.

  • Unique interactive ratio normalisation facility – allows user to optionally correct fluorochrome ratio.to be used as the diploid ratio.

  • Unique two scale gain and loss bars showing user defined values of amplification and deletion.

  
Courtesy of Dr Tanja Hardt and Dr Evelin Schrock, Tumor Genetics and Molecular Cytogenetics, Institute of Medical Genetics, CHarite, Humboldt University, Berlin, Germany